Ikorel 5mg Tablets

Nicorandil is a vasodilatory drug used to treat angina. Angina is chest pain that results from episodes of transient myocardial ischemia. This can be caused by diseases such as atherosclerosis, coronary artery disease and aortic stenosis. Angina commonly arises from vasospasm of the coronary arteries. There are multiple mechanisms causing the increased smooth muscle contraction involved in coronary vasospasm, including increased rho-Kinase activity. Increased levels of rho-Kinase inhibit myosin phosphatase activity, leading to increased calcium sensitivity and hypercontraction. [1] rho-Kinase also decreases nitric oxide synthase activity, which reduces nitric oxide concentrations. [2] lower levels of nitric oxide are present in spastic coronary arteries. [3] l-Type calcium channel expression increases in spastic vascular smooth muscle cells, which could result in excessive calcium influx, and hypercontraction. [4]
Equivalent Brands:
Ikorel 5mg Tablets equivalent/ substitute for brands Adancor, Angedil, Angicor, Aprior, Av-Cor, Corangi, Cordinik, Corflo, Dancor, Ikorel, Ikotril, K-Cor, Nicodil, Nicoduce, Nicolan, Nicoline, Nicor, Nicoral, Nicostar, Nidil, Nikoran, Nikoranmart ), Nirandil, Randil, Sigmart, Silvinol, Zynicor, Nikoran, Nicostar, Korandil, Nicordil,uses=Ikorel Contains The Active Substance €�Nicorandil€¯. This Belongs To A Group Of Medicines Called€�Potassium Channel Activators€™.Ikorel Is Used To Prevent Or Reduce Painful Signs (€�Angina Pectoris€¯) Of Your Heart Disease. It Is Used Inadults Who Cannot Take Heart Medicines Called €�Beta-Blockers€¯ Or €�Calcium Antagonists€¯.Ikorel Works By Increasing The Blood Flow Through The Blood Vessels Of The Heart. It Improves Theblood And Oxygen Supply Of Your Heart Muscle And Reduces Its Workload.